BRCA AND BREAST AND OVARIAN CANCERS

Collection Instr. …………: – Fasting not required.

Technical Information: The search for alterations in the BRCA gene can be done by two methods: 

(a)Sequencing, which allows a comprehensive analysis of the genome and the detection of the most frequent alterations. This method is more usually indicated for people who have no knowledge of any family mutation. 

b)Complete sequencing with MLPA, which consists of the complete study of the DNA and the analysis of the BRCA1 and BRCA2 genes by the MLPA technique, a technology of great efficiency and able to detect even less frequent alterations, with the minute view of the analyzed region.